{"title":"Animal Health","description":"\u003cp\u003eKI Screening Test\u003c\/p\u003e","products":[{"product_id":"ki-screening-test-800087-5","title":"KI Screening Test (5Pk. Product Code: 800087-5)","description":"\u003cp\u003e\u003cspan\u003eThe first rapid test for semi-quantitative detection of NGAL in urine for early screening of kidney damage in dogs\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 class=\"text-veterinary\"\u003e\u003cbr\u003e\u003c\/h2\u003e\n\u003ch2 class=\"text-veterinary\"\u003eNGAL PROTEIN\u003c\/h2\u003e\n\u003cdiv class=\"px-3\"\u003e\n\u003cp\u003e\u003cstrong\u003eNeutrophil Gelatinase Associated Lipocalin\u003c\/strong\u003e (NGAL), a protein synthesised by many tissues, is freely filtered by the glomeruli and reabsorbed by renal tubules. Tubular damage results in increased NGAL in the urine due to reduced reabsorption of the filtered NGAL from the plasma and an increased release of NGAL from damaged proximal and distal tubules.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv id=\"more01\" class=\"collapse show\"\u003e\n\u003cdiv class=\"px-3 pt-2\"\u003e\n\u003cp\u003eThe role of \u003cstrong\u003eNGAL as an early marker of Acute Kidney Injury\u003c\/strong\u003e (AKI), Chronic Kidney Disease (CKD) and Urinary\u003cbr\u003eTract Infection (UTI) has been the subject of recent studies in dogs, which confirm its clinical utility and prognostic role in enabling \u003cstrong\u003erapid therapeutic intervention\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2 class=\"text-veterinary\"\u003eWHO IS THIS TEST FOR?\u003c\/h2\u003e\n\u003cdiv class=\"px-3\"\u003e\n\u003cp\u003eKI SCREENING TEST is a lateral flow immunochromatographic device, for professional use, for \u003cstrong\u003esemi-quantitative detection of NGAL\u003c\/strong\u003e in dog urine samples. It can be used by veterinary professionals in order to \u003cstrong\u003eearly detect the presence of kidney injuries in dogs\u003c\/strong\u003e in just 10 minutes.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv id=\"more02\" class=\"collapse show\"\u003e\n\u003cdiv class=\"px-3 pt-2\"\u003e\n\u003cp\u003eBy comparing the intensity of the test line (T) with the colour chart provided, the concentration of NGAL in the urine can be semi-quantitatively detected, which is directly proportional to the severity of kidney damage and \u003cstrong\u003eindicative of potential clinical settings\u003c\/strong\u003e.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2 class=\"text-veterinary\"\u003ePERFORMANCE STUDIES AND TECHNICAL SPECS\u003c\/h2\u003e\n\u003cdiv class=\"px-3\"\u003e\n\u003cp\u003e\u003cstrong\u003eCLINICAL\u003c\/strong\u003e\u003cbr\u003eWhen used in the setting of a clinical trial on dogs, the device showed that a urinary NGAL concentration of 20 ng\/mL was the cutoff capable of distinguishing the presence of AKI, with a sensitivity of 97.6%. The device was therefore found to be a \u003cstrong\u003eclinically relevant diagnostic tool\u003c\/strong\u003e for identifying the risk of AKI in the clinical setting.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eANALYTICAL\u003c\/strong\u003e\u003cbr\u003eThe test was evaluated on 180 urine samples from different clinical settings of urinary tract disease by comparing it with the gold standard (ELISA, BioPorto Diagnostics inc).\u003cbr\u003eThe analytical performance, understood as the ability of the device to detect the presence of NGAL above the Limit of Detection (LoD), measured were as follows:\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cem\u003e\u003cspan class=\"s1\"\u003eSpecificity\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003e98.15%\u003c\/span\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cem\u003e\u003cspan class=\"s1\"\u003eSensitivity\u003cspan class=\"Apple-converted-space\"\u003e  \u003c\/span\u003e99.21%\u003c\/span\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e\u003cem\u003e\u003cspan class=\"s1\"\u003eAccuracy\u003cspan class=\"Apple-converted-space\"\u003e    \u003c\/span\u003e98.9%\u003c\/span\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e \u003c\/p\u003e\n\u003cp class=\"p1\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"text-veterinary\"\u003eTEST KIT COMPONENTS\u003c\/h2\u003e\n\u003cp class=\"p1\"\u003e\u003cspan class=\"s1\"\u003eX1 Test Cassette\u003cbr\u003eX1 Vial with dropper containing the diluent\u003cbr\u003eX1 Pipette for urine sampling\u003cbr\u003eX1 Comparative card\u003cbr\u003eX1 Instructions For Use (IFU)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"p1\"\u003e \u003c\/p\u003e\n\u003ch2 class=\"text-veterinary\"\u003eTEST PROCEDURE\u003c\/h2\u003e\n\u003col\u003e\n\u003cli class=\"p1\"\u003e\n\u003cspan class=\"s1\"\u003e\u003c\/span\u003e\u003cspan class=\"s1\"\u003eCollect the urine sample;\u003c\/span\u003e\u003cspan class=\"s1\"\u003e\u003cbr\u003e2. Deposit the collected sample into the vial, previously opened, and mix the solution;\u003cbr\u003e3. Add the obtained liquid into the sample well (S) indicated on the cassette and wait 10 minutes;\u003cbr\u003e4. Read the result by comparing the lines obtained with the card provided.\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2 class=\"text-veterinary\"\u003eINTERPRETING THE RESULTS\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNGAL \u0026lt; 4 ng\/mL\u003c\/strong\u003e: no kidney damage.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNGAL ~4 ng\/mL\u003c\/strong\u003e: low risk of acute kidney injury.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNGAL ~20 ng\/mL\u003c\/strong\u003e: intermediate risk of acute kidney injury. Consider the possible presence of CKD (Chronic Kidney Damage) or UTI (Urinary Tract Infections) in differential diagnostics.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNGAL \u0026gt; 90 ng\/mL\u003c\/strong\u003e: high risk of acute kidney injury or chronic kidney damage.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2 class=\"text-veterinary\"\u003eADDITIONAL INFORMATION\u003c\/h2\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch6 class=\"text-veterinary\"\u003e\u003cstrong\u003e1. CLICK \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0653\/9952\/1445\/files\/KI_SCREENING_TEST_Presentation_CCSupplies.pdf?v=1785138031\" title=\"NGAL SCREENING TEST PRESENTATION\"\u003eHERE\u003c\/a\u003e FOR PRODUCT PRESENTATION\u003c\/strong\u003e\u003c\/h6\u003e\n\u003ch6 class=\"text-veterinary\"\u003e\u003cstrong\u003e2. CLICK \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0653\/9952\/1445\/files\/800087-5_LEAFLET_02_4-0-1.pdf?v=1785138030\" title=\"NGAL SCREENING TEST FLYER\"\u003eHERE\u003c\/a\u003e FOR PRODUCT FLYER\u003c\/strong\u003e\u003c\/h6\u003e\n\u003ch6 class=\"text-veterinary\"\u003e\u003cstrong\u003e3. CLICK \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0653\/9952\/1445\/files\/800087_IFU_106_9-0__RA_Ok.pdf?v=1785138029\" title=\"NGAL SCREENING TEST IFU\"\u003eHERE\u003c\/a\u003e FOR INSTRUCTIONS FOR USE (IFU)\u003c\/strong\u003e\u003c\/h6\u003e\n\u003ch6 class=\"text-veterinary\"\u003e\u003cstrong\u003e4. CLICK \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0653\/9952\/1445\/files\/Q8R617-1_Clinical_Validation_Report_KI_Screening_Test.pdf?v=1785138889\" title=\"NGAL SCREENING TEST CLINICAL STUDY\"\u003eHERE\u003c\/a\u003e FOR CLINICAL STUDY\u003c\/strong\u003e\u003c\/h6\u003e\n\u003ch6 class=\"text-veterinary\"\u003e\u003cstrong\u003e4. CLICK \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0653\/9952\/1445\/files\/DPR065-1_Product_Data_NGAL.pdf?v=1785138921\" title=\"NGAL SCREENING TEST CLINICAL VALIDATION REPORT\"\u003eHERE\u003c\/a\u003e FOR CLINICAL VALIDATION:  SENSITIVITY, SPECIFICITY \u0026amp; ACCURACY \u003c\/strong\u003e\u003c\/h6\u003e\n\u003ch6\u003e\u003cbr\u003e\u003c\/h6\u003e\n\u003ch6\u003e\u003c\/h6\u003e\n\u003c\/div\u003e","brand":"SupaMedPro - Wholesale Medical Supplies - Australia","offers":[{"title":"Default Title","offer_id":48056784617637,"sku":null,"price":0.0,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0653\/9952\/1445\/files\/IMG_0374.jpg?v=1785137638"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0653\/9952\/1445\/collections\/IMG_0374.jpg?v=1785140535","url":"https:\/\/supamedpro.com.au\/collections\/animal-health.oembed","provider":"SupaMedPro - Wholesale Medical Supplies - Australia","version":"1.0","type":"link"}